MANAGING ADOLESCENT ACNE THROUGH DIETARY CONTROL: AN ALTERNATIVE TO ACCUTANE

บทคัดย่อ

This study explores dietary intervention as a potential alternative to conventional pharmacological treatment for adolescent acne vulgaris. A mixed-methods design was employed, combining a literature review, structured questionnaires, and two observational case studies. The sample consisted of 50 adolescents aged 13–18 years with moderate to severe acne.

Findings revealed significant associations between high-glycemic diets, dairy intake, and increased acne severity. Participants following a ketogenic-inspired dietary approach exhibited a mean reduction in Global Acne Grading System (GAGS) scores from 24.26 ± 3.61 to 16.48 ± 2.46—representing an average 32% improvement. Additionally, 73% of participants who reduced high-sugar foods reported clinical improvement in acne symptoms, while 67% of those who eliminated dairy noted enhanced skin clarity.

The observed benefits are likely mediated through hormonal and metabolic mechanisms, including suppression of insulin/IGF-1 signaling, inhibition of mTORC1 pathways, reduced inflammation, and improved gut microbiota balance. Beyond physiological improvements, participants reported psychosocial benefits such as increased self-confidence and reduced social withdrawal.

These results support the integration of dietary counseling—specifically targeting glycemic load and dairy intake—as a complementary strategy in acne management. Further randomized controlled trials with larger sample sizes are warranted to validate the long-term efficacy and safety of dietary protocols in dermatological care.